Interactive health diagram

Depression and the gut-brain axis

Explore how mood symptoms can connect with gut signals through nervous, immune, endocrine, and microbial pathways.

Brain Gut

Neural pathway

Depression can change gut-brain signaling.

Depression is linked with changes in sleep, appetite, stress reactivity, and autonomic tone. Those shifts can affect digestion and gut signaling, while gut signals may also feed back into mood regulation.

Educational diagram only. It does not diagnose, treat, or replace medical care. Mental health symptoms deserve support from a qualified clinician.